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3 . 2017

Hydro-lazes of umbilical cord blood in newborn digestive potential characteristics

Abstract

Enzymatic digestive potentiaL of newborn is one of indices of its functionaL abiLity to Lactotrophy. HydroLase of newborn and puerpera umbiLicaL cord bLood serum with normaL (36) and incompLete (40) gestation periods were determined: α-amyLase, Lipase (coLorimetric method according to Roche instruc­tion reagent set), pepsinogen I and II (chemiLuminicsent immunoassay method with Abbot reagent set).

At a normaL gestation period the hydroLase content in umbiLicaL cord bLood serum was Lower than in puerpera bLood serum: Lipase and α-amyLase in three times, pepsinogen I aLmost in 4.6 times, pepsinogen II onLy in 1.6 times. It indicates that periods of different enzymatic system formation differ.

In umbiLicaL cord bLood a premature newborn in comparison with normaL newborn dispLayed decreasing of amyLase content from 9.0 to 4.6 Unit/L, pepsinogen I content from 11.0 to 4.,7 mkg/L, pepsinogen II content from 5.5 to 3.4 mkg/L, but Lipase content was not change. It is proved that fetaL LipoLysis system is formed earLier.

HydroLytic enzyme content of digestive gLand in umbiLicaL cord bLood serum is an informative test of newborn digestive potentiaL.

Keywords:newborn, cord blood, hydrolases, digestive potential

Neonatology: News, Opinions, Training. 2017; (3): 97-102.
DOI: 10.24411/2308-2402-2017-00044


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CHIEF EDITOR
CHIEF EDITOR
Degtyarev Dmitriy Nikolaevich
Doctor of Medical Sciences, Professor, Deputy Director for Scientific Research of the V.I. Kulakov Obstetrics, Gynecology and Perinatology National Medical Research Center of Ministry of Healthсаre of the Russian Federation, Head of the Chair of Neonatology at the Clinical Institute of Children's Health named after N.F. Filatov, I.M. Sechenov First Moscow State Medical University, Chairman of the Ethics Committee of the Russian Society of Neonatologists, Moscow, Russian Federation

ORCID iD 0000-0001-8975-2425

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