Meta-analysis shows that infants who have suffered neonatal sepsis face an increased risk of mortality and severe complications

• S.E. Bakhuizen
• de Haan T.R.
• M.J. Teune
• A.G. van Wassenaer-Leemhuis
• J.L. van der Heyden
• D.P. van der Ham
• B.W.J. Mol

Abstract

Infants suffering from neonatal sepsis face an increased risk of early death and long-term neurodevelopmental delay. This paper analyses and summarises the existing data on shortterm and long-term outcomes of neonatal sepsis, based on 12 studies published between January 2000 and 1 April 2012 and covering 3,669 neonates with sepsis. Conclusion: infants who have suffered neonatal sepsis face an increased risk of mortality and severe complications such as brain damage and, or, neurodevelopmental delay.

Acta Paediatrica. 2014. Vol. 103. Р. 1211–1218. doi:10.1111/apa.12764

Keywords:neonatal sepsis, morbidity, mortality, outcome, prognosis