Dynamics of cardiorespiratory and echocardiographic parametres in infants with bronchopulmonary diplasia

• Solomakha Anna Yu.
• Petrova Natalia A.
• Obraztsova Galina I.
• Ivanov Dmitry O.
• Sviryaev Yurii V.

Abstract

Premature infants with bronchopulmonary dysplasia (BPD) need cardiorespiratory monitoring during the first year of life, since longer apnea persistence may have negative effect on the course of the disease. Dynamics of echocardiography parameters is also very important because there is a tendency to pulmonary artery pressure increase, which can lead to pulmonary hypertension (PH).

The aim of the study was to evaluate the dynamics of cardiorespiratory and echocardiography parameters in premature infants with BPD.

Material and methods. Cardiorespiratory monitoring and echocardiography were performed in 11 infants born at 24 0/7-29 0/7 weeks gestation, with birth weight <1400 grams and had BPD, at two age periods: at 35-41 weeks of postmenstrual age (PMA) before discharge from the hospital and at 9-10 corrected months of life (71-87 weeks of PMA). Of them three infants were diagnosed PH.

Results. The average SpO₂ was satisfactory at both age periods. Desaturation index, number of desaturation episodes <10% were decreased in secondary examination. There was a strong tendency to apnea/hypopnea index decrease. We did not find difference in indexes of each type of apnea between these age periods. There was a significant decrease in the mean pulmonary artery pressure, the absence of regurgitation and hemodynamic overload of right ventricle at the second echocardiography. In our study, any infants did not have the right atrium dilation and flattening of the interventricular septum. There was also no association between the occurrence of obstructive apnea and increase in mean pulmonary artery pressure.

Conclusions. The positive dynamics of cardiorespiratory and echocardiographic indices in infants in 9-10 corrected months of life was marked.

Keywords:prematurity, bronchopulmonary dysplasia, pulmonary hypertension, apnea, cardiorespiratory monitoring, echocardiography

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)